Psoriasis. Discover The Full Guide Of Symptoms, Treatments, And Causes

    Disease-knows-no-boundaries-nor-skips-Celebrities-Psoriasis-causes-and-treatment-by-piplum
    Psoriasis disease knows no boundaries nor skips celebrities.

    According to psoriasis.org — Psoriasis typically affects the outside of the elbows, knees or scalp, though it can appear on any location.

    Some people report that psoriasis is itchy, burns and stings.

    Psoriasis is associated with other serious health conditions, such as diabetes, heart disease and depression.

    Psoriasis is a chronic disease — it means that it lasts 1 year or more and require ongoing medical attention or limit activities of daily living or both.

    It is benign and not contagious.

    The cause of psoriasis is unknown.

    It is not contagious but often occurs in certain families.

    The disease typically appears for the first time in young adulthood with red, thickened skin areas covered with white scales.

    Commonly, the knees and elbows are affected, but psoriasis can appear anywhere on the skin.

    Sometimes you can be misleaded:

    If you’re experiencing uncomfortable patches, scales, or redness on your skin, you may be wondering if you have psoriasis or rosacea. (About rosacea you can read in this article: What Triggers Rosacea? How To Fight Symptoms and Treat This Disease.

    Even most famous people like Kim Kardashian West can’t rid of psoriasis. Her quote about this disease:

    If you have psoriasis, you can’t let it ruin your life or get the best of you. @KimKardashian

    Celebrity-Kim-Kardashian-West-Has-Psoriasis
    ”Psoriasis is the shi*s”. Kim Kardashian West is fighting with psoriasis.

    Cara Delevingne, an in-demand model says that she has this disease. Here are some quotes from her:

    • ”Just to reiterate, I have psoriasis and it’s leaves scares and I will have for the rest of my life [sic]”
    • ”I can handle the negative comments but just remember that no one is perfect.”
    • EMBRACE YOUR INDIVIDUALITY! It makes you who you are x.”

    It only happened during the Fashion Weeks, which are, of course, the worst time of year for me to be covered in scabs. Psoriasis is an auto-immune disease, and I’m sensitive. @Cara Delevigne.

    Model-Actress-Cara-Delevingne-Psoriasis-quote
    Cara Delevingne, who fights psoriasis says that no one is perfect.

    What Are The Most Common Causes of Psoriasis. 

    In psoriasis skin, the cells of the epidermis divide approximately 7 times faster than normal.

    Although Psoriasis has nothing to do with cancer, but according to Harvard Medical School it still can cause some types of cancer:

    The researchers found that people with psoriasis had an increased risk of developing cancers including colon, kidney, laryngeal, liver, lymphoma, non-Hodgkin lymphoma, esophageal, oral, and pancreatic cancers.

    Worth reading: How to Reduce Your Risk of Breast Cancer. [Info Graphic]

    They also found that people with severe psoriasis who developed cancer also had an increased overall risk of dying.

    The rapid cell division is accompanied by decreased cell maturation.

    This entails a heavy scale formation.

    The-most-common-symptoms-of-psoriasis-are-skin-rashes-or-red-patches
    The most common symptoms of psoriasis are skin rashes or red patches

    The rapid cell division and insufficient cell maturation are caused by signal substances released from white blood cells (lymphocytes).

    The activation of lymphocytes is probably essential for the development of psoriasis.

    What Worsens Psoriasis? The Most Common Aggravating Factors.

    Psoriasis can occur on areas of skin that are damaged by scratching, rubbing or severe sunburns.

    Similarly, certain infections, particularly streptococcal throat infection, can cause a new outbreak or aggravate an existing outbreak.

    Stress and alcohol consumption are also common aggravating factors.

    You might like: Gestational Diabetes? The Best Way To Deal With Pregnancy Risks.

    Certain medications such as lithium, beta-blockers and anti-malarial drugs can sometimes induce an aggravation.

    The disease is also influenced by climate.

    It is common for the disease to worsen during winter and improve during summer

    Psoriasis-can-worsen during-winter and improve during summer
    Psoriasis can worsen during winter and improve during summer

    Different types of Joint and Nail Psoriasis. 

    Psoriasis appears in a variety of forms.

    Nails and joints can be attacked.

    The most common form appears with red, thickened areas that are covered with thick, white scales.

    These areas are well-demarcated in relation to the normal skin, but the affected areas can flow together.

    All skin areas can be attacked, but many patients experience the affection of knees and elbows.

    It is common for both the right and left sides to be attacked at the same time.

    The disease is also commonly appearing in the scalp area causing annoying dandruff formation.

    For some, especially overweight patients, the disease can occur in the skin folds.

    The heavy scale formation is rarely seen in the skin folds.

    Nail Psoriasis

    When the nails are attacked, it manifests itself with small indentations in the nail plate (called ‘pittings’) or partial loosening of the nail.

    This loosening causes a yellow discoloration.

    Nail-Psoriasis-causes-remedies-healing-treatments-drugs
    Psoriatic nail disease has many clinical signs.

    In the most severe cases, the nail plate thickens or crumbles.

    Approximately 50% of patients with psoriasis have some nail involvement, and the lifetime incidence of nail disease is estimated at 80% to 90%.

    Nail disease may rarely be the only manifestation of psoriasis.

    More important, nail psoriasis can cause significant pain and discomfort, leading to impairment in quality of life and work function.

    There is a strong correlation of nail psoriasis with psoriatic arthritis.

    Patients with psoriatic arthritis have rates of nail disease as high as 70%.

    There is evidence that nail psoriasis may be a predictor of the joint disease developing later in life.

    Fingernail psoriasis is more problematic for many patients than toenail disease.

    In addition, psoriatic toenails are often secondarily infected with dermatophytes, which may complicate treatment assessment.

    Treatment with immunosuppressive medications may even contribute to the development of onychomycosis in patients with toenail psoriasis.

    For these reasons, most studies evaluate fingernail psoriasis alone.

    Nail Psoriasis Treatment

    An array of treatment options are available for nail psoriasis, including topical products, procedural interventions, and oral-systemic and biologic agents.

    The challenges of treating nail disease are poor penetration of topical therapy into the nail and surrounding tissue, pain associated with intralesional injections, adverse effects, and monitoring of systemic therapies and patient adherence to therapy.

    Because many of the treatments most commonly used to treat psoriasis do not have published, randomized, double-blind, placebo-controlled trials addressing nail disease, the recent Cochrane review does not help dermatologists make an informed decision regarding the best treatment for a patient with nail psoriasis.

    Nail Psoriasis Treatment Recommendations:

    Treatment recommendations for 4 clinical nail psoriasis scenarios were developed based on the evidence reviewed in the study and expert opinion from the Medical Board of the National Psoriasis Foundation.

    1. Patients with psoriasis limited to the nails. These patients have minimal or no skin disease and no evidence of joint disease, with 3 of 10 fingernails having onycholysis, pitting, and distal hyperkeratosis. These patients are embarrassed by the appearance of the nails and have mild pain with use. No previous therapy has been used. High-potency topical corticosteroids alone or in combination with calcipotriol were recommended with enthusiasm, and intralesional corticosteroidswere recommended.Systemic and biologic treatments were not recommended for this patient scenario.
    2. Patients with psoriasis limited to the nails for whom topical therapy has failed. These patients have 5 of 10 nails involved and moderate to severe nail pain. The medical board recommended the following in ranking order from highest enthusiasm to lowest: adalimumab, etanercept, intralesional corticosteroids, ustekinumab, methotrexate, and acitretin.
    3. Patients with psoriasis of the skin and nails. These patients have psoriasis on 8% of their body surface area, 5 of 10 nails with severenaildystrophy,andmoderate to severenail associatedpain. Topical therapies have proven inadequate to control disease. The board recommended adalimumab, etanercept, and ustekinumab with high enthusiasm; methotrexate, acitretin, infliximab, and apremilast were also recommended.
    4. Patients with skin, joint, and nail disease. These patients have skin disease on 8% of their body surface area, a history of dactylitis and morning stiffness (psoriatic arthritis), and 5 of 10 nails with severe nail involvement and pain. The recommendations for treatment were, in ranked order from the highest to lowest: adalimumab, etanercept, ustekinumab, infliximab, methotrexate, apremilast, and golimumab.

    Rare Forms of Psoriasis

    Especially with young people, a certain form of psoriasis can occur following a throat infection.

    This form appears with large drop-shaped, red bumps which can attack large areas of the skin.

    It is common for such acute outbreaks to disappear after a few weeks.

    In addition to these common forms of psoriasis, rare pustular psoriasis also exists.

    It is characterized by red skin areas dotted with yellow pus-filled blisters.

    This form of psoriasis is not contagious either.

    Psoriatic Arthritis. Facts and Treatment.

    About 20% of patients with psoriasis suffer from a special form of psoriatic arthritis.

    Psoriatic-arthritis-typically-affects-the-large-joints
    Psoriatic arthritis typically affects the large joints

    Psoriatic arthritis can usually be diagnosed by examining its distribution in the joints and on the x-rays changes

    Psoriatic arthritis is a chronic inflammatory skeletal disease associated with health concerns such as obesity, type II diabetes, dyslipidemia, hypertension, and cardiovascular disease.

    The role of these metabolic factors in the pathogenesis, severity, and progression of psoriatic arthritis remains unclear.

    Psoriatic-Arthritis-Treatment-and-Facts-Sheet-For-Patients
    Psoriatic Arthritis Treatment and Facts Sheet For Patients. Source: www.rheumatology.org

    Diagnosing Psoriatic Arthritis

    Early recognition, diagnosis and treatment of psoriatic arthritis can help prevent or limit the extensive joint damage that occurs in later stages of the disease.

    psoriatic-arthritis-affects-on-the-body-and-symptoms-infographic-poster-list-remedies
    Psoriatic arthritis affects and symptoms

    How is Psoriasis diagnosed?

    A doctor can usually diagnose psoriasis by examining the skin.

    In case of doubt, a skin sample is taken which is then examined under a microscope.

    The diagnosis cannot be made based on a blood sample.

    How is the Psoriasis Disease Treated? Treatment Drugs and Tips.

    Psoriasis cannot be cured. But there are some effective remedies to reduce symptoms.

    Here are tips how to treat Psoriasis:

    • Sun exposure
    • Baths
    • Probiotics
    • Occlusive dressings
    • Topical preparations for psoriasis
    • Emollients
    • Topical steroids 
    • Vitamin D-like compounds
    • Tar 
    • Dithranol 
    • Calcineurin inhibitors
    • Tazarotene
    • Ultraviolet treatment for psoriasis
    • Narrow ultraviolet B 
    • Psoralen and ultraviolet A 
    • Systemic non-biological medication for psoriasis
    • Methotrexate 
    • Ciclosporin
    • Acitretin 
    • Apremilast
    • Fumaric acid esters
    • Other non-biological medications
    • Biological therapies

    Topical treatment, systemic treatment (tablet or injections) and phototherapy can be used to keep psoriasis at rest.

    Since the disease has many different degrees of severity, the treatment of psoriasis is carried out according to the individual patient’s needs.

    In addition, the disease sometimes varies to such an extent that each individual patient may need to be given different treatments at different times.

    There is no treatment able to cure the disease. Don’t be hooked on the fake ads!

    The purpose of the treatment is, therefore, to make current outbreaks disappear.

    A distinction is made between topical treatment, phototherapy, tablet treatment, and biological treatment.

    In addition, these treatments can be given in different combinations.

    In most cases, the treatment is carried out at home, while there is rarely a need for hospitalization.

    Steroids (adrenocortical hormone preparations)

    Steroids come in various strengths both as an ointment, cream, gel, and solution.

    The strong preparations have a rapid effect; but they also have side effects including thin skin, enlarged blood vessels and the tendency of superficial skin hematomas after prolonged use.

    By following the doctor’s treatment instructions, side effects can most often be avoided. The side effects are most often visible in the face and on skin folds.

    Be aware that sudden cessation, especially with the strong preparations, may cause a transient aggravation of the disease.

    Combination of vitamin D and steroids

    An ointment containing both a steroid and calcipotriol (Daivobet®) is more effective than each drug alone.

    Treatment with this kind of combination is suitable for many patients.

    Coal Tar For Skin Treatment

    Tar is one of the oldest known preparations used for treating psoriasis.

    Topical application of coal tar has been used to treat skin diseases for more than 2000 years is an effective therapy for reducing skin inflammation and itch while improving the skin barrier function.

    Tar-coal-is-used-for-psoriasis-treatment
    Tar coal is getting more popular for psoriasis treatment. Source: www.health-holland.com

    Tar smells and discolours, and it can increase the skin’s sensitivity to sunlight, but the tar treatment is without major side effects.

    It is a well-known fact that tar in certain contexts can be carcinogenic, but numerous studies have shown that tar treatment of psoriasis patients do not result in an increased risk of developing skin cancer.

    Tar can be used in both ointments and pastes, but pure tar can also be smeared on the skin.

    This treatment can be combined with a hot shower.

    Tar baths are especially used during hospitalisation at a dermatology department.

    Phototherapy. Sunlight For Psoriasis Treatment. 

    Different types of ultraviolet light, sometimes in combination with tablets (PUVA), can improve psoriasis.

    The ultraviolet rays in sunlight can improve psoriasis symptoms.

    Dr. Julie Moore of Gottlieb Memorial Hospital says that sunlight is one of the best ways to treat psoriasis, so she recommends that her patients “sit out on the deck and give their affected areas a good sun bath.

    The-ultraviolet-rays-in-sunlight-can-improve-psoriasis-symptoms-tan-to-heal-skin-disease
    Might be that sunlight is one of the best ways to treat psoriasis

    The same ultraviolet rays can be formed in fluorescent tubes of different types.

    Some tubes produce ultraviolet light of type B (UVB).

    This kind of ultraviolet light improves psoriasis after approx. 30 treatments given 2-3 times weekly.

    During the treatment period, the amount of light is gradually increased in order to accustom the skin to the ultraviolet rays.

    UVB treatment can be given by practising dermatologists and at dermatology departments.

    PUVA is another kind of phototherapy.

    P stands for psoralen which is a substance that increases the skin’s sensitivity to ultraviolet light.

    UVA stands for ultraviolet light of type A.

    When receiving PUVA treatment, the patient should take psoralen tablets prior to UVA irradiation.

    Psoralen accumulates in the lens of the eye.

    In order to avoid eye side effects, sunglasses must be worn when staying outdoors in the sunshine on the day of treatment.

    Tanning solariums emit almost pure UVA radiation.

    So, if you are using solariums for psoriasis treatment, you need to be aware of that there is no such thing as a safe tan from a solarium.

    There-is-no-such-thing-as-a-safe-tan-from-a-solarium-psoriasis-treatment-remedies
    There is no such thing as a safe tan from a solarium

    It is a myth that using a solarium is a safe way to tan and protects your skin from burning in the sun.

    Solarium tans offer no protection against DNA damage to skin cells, which can occur without any visible signs of skin damage. 

    The effect of solarium treatment on psoriasis is limited.

    Prolonged, intense exposure to ultraviolet light can increase the risk of premature aging of the skin and the development of skin cancer.

    With the knowledge we have today, it seems, however, that the use of ultraviolet light as treatment only increases the risk of skin cancer on a very low level.

    The types of skin cancer that can occur are slow growing and can be cured.

    Tablet treatment

    Tablet treatment with methotrexate, acitretin (Neotigason®) or ciclosporin (Sandimmun®) is used to treat severe psoriasis.

    Tablet treatment is used in rare cases and only for psoriasis patients for whom other treatments have not had an effect.

    Tablet-treatment-psoriasis-cure-medicine-drugs-skin-help-problems
    In some cases, tablet treatment can help fighting psoriasis.

    Acitretin is related to vitamin A.

    More about vitamins-rich food read here: Do You Really Know The Truth About the Food You Eat? [11 Myths]

    Acitretin can result in a significant improvement, but this improvement is often accompanied with side effects, especially in terms of dryness and flaking of the mucous membranes; just as there can be seen an impact on the liver function and an increase of the content of certain fats in the blood.

    It is therefore important to arrange regular consultations with the doctor during an acitretin treatment.

    Acitretin is teratogenetic and is slowly excreted from the organism.

    It is thus important that women are protected against pregnancy during and following treatment.

    Methotrexate is a so-called cell poison.

    With psoriasis, methotrexate is given in such small quantities that only the immune system is affected.

    Wow to strengthen immune system read here: Discover Immune and Nervous System Strengthening oil – Flaxseed Oil

    Methotrexate is one of the most effective means for treatment of psoriasis.

    When initiating a methotrexate treatment, blood samples must be taken once a week.

    Later on, monthly blood samples will be sufficient.

    Ciclosporin affects the immune system of the organism, and it therefore has a very good effect on even severe psoriasis outbreaks.

    However, treatment with ciclosporin can increase blood pressure and decrease the renal function.

    Therefore, ciclosporin is not suitable for long-term treatment.

    Biological treatment

    Biological drugs are proteins, usually antibodies, specifically designed to affect the activation of the immune system in the skin.

    Compared to traditional treatment, biological therapy can have similar or even fewer side effects.

    Psoriasis-biological-treatment-usually-affects-the-immune-system
    Psoriasis biological treatment usually affects the immune system

    The treatment is expensive.

    So far these drugs are approved for treatment of severe psoriasis which cannot be satisfactorily treated in any other way:

    The biological substances are given as an injection either in a vein (at the hospital) or beneath the skin (by the patient him/herself).

    Climate therapy

    Climate therapy can sometimes be chosen over hospitalisation.

    Climate therapy lasts 4 weeks and is commonly carried out at the Dead Sea in Israel.

    People-use-Dead-Sea-mud-to-treat-health-conditions-ranging-from-psoriasis
    Dead Sea mud can relieve pain, reduce inflammation, and symptoms of Psoriasis

    The most important part of the treatment is the sunbeams which especially in this geographic area contain many UVA rays.

    In addition, the patients bathe in the Dead Sea which has a very high salt content.

    Climate therapy often results in total improvement of the skin; however, as with the other treatments, psoriasis will reappear at one time or another.

    Some places like Blue Lagoon in Iceland tells that the efficacy of Blue Lagoon geothermal seawater for treating psoriasis has been confirmed through decades of research.

    Psoriasis-triggers-geothermal-seawater-a-resource-with-scientifically-proven-healing-benefits-blue-lagoon
    Bathing in geothermal seawater gives you a scientifically proven healing benefit — reduce symptoms of Psoriasis: bluelagoon.com

    Experimental treatment. Leech therapy.

    Extensive research is being conducted in the field of psoriasis, and new treatments are being tested.

    However, the road from the first testing of a new product to its availability at the pharmacy is long.

    age-old-medical-device-leeches-skin-cure
    Age-old medical device for psoriasis — leeches

    These are a few of the clinical success stories with leeching.

    Its effect on venous congestion packed with its bio molecules is definite to show more wonderful effects on other dermatological problems as well.

    Skin disorders primarily of autoimmune kind make the dermis thick with poor tissue perfusion.

    The leech saliva prevents inflammatory mediators, decreases tissue thickness, accelerates reperfusion, and increases permeability of the tissue making it more acceptable to therapeutics. Hence making leech therapy an ideal mode of treatment in
    dermatology.

    Leech is a boon to the dermatologists but its use must be with caution as it’s known to have its own type of side effects.